Isolation and Characterization of Antibiotic Producing Fungi from Soil

This study was aimed to isolate and characterize antibiotic producing fungi from the soil environment within Ahmadu Bello University main campus Samaru, Zaria. Soil samples were collected five different locations for Isolation of fungi. Spread plate method involving serial dilution technique used using Saboraud Dextrose Agar (SDA). Six species isolated then characterized microscopically macroscopically. The Aspergillus niger, fumigatus, sp, Penicillium Fusarium sp (P14) (P15). Sensitivity test Staphylococcus aureus, Escherichia coli Klebsiella pneumoniae as pathogens employed determine ability fungal isolates produce antimicrobials. All found inhibit growth at least one except (P14). niger produces zones inhibition 9mm, 5mm 6mm against coli, pneumoniae, fumigatus pneumoniae. produced aureus which a zone 10mm, 7mm findings this show that antibiotic-producing fungus are prevalent in University's Zaria, these strains could be by pharmaceutical companies antibiotics local sources.